Transplantation can help diabetics

Pancreas tran­sp­l­a­n­­­­tation is now being cons­idered for type 1 dia­b­etics

By :  uma kannan
Update: 2014-01-19 10:50 GMT
(From left) Ambika Mammen and K.M. Mammen, chairman and MD of MRF, interact with Dr Prithvi Mohandas and his parents Dr P.V.A Mohandas and Mallika Mohandas at the inauguration of department of transfusion medicine at MIOT International on Saturday.

Chennai: With technological adv­a­ncement and better immu­nosuppressive dr­ugs, pancreas tran­sp­l­a­n­­­­tation is now being cons­idered for type 1dia­b­etics to give them comp­lete insulin inde­p­e­n­­d­e­nce. A study points out that nearly 75 per cent of pancreas transplantati­ons are perfor­m­ed with kidney transp­l­­antations and in pat­ients with re­nal failure.

In India, the first successful simultaneous pa­n­­­creas-kidney transpl­ant was reported in 2005. Type 1 diabetes is seen mostly in the you­nger po­­pulation, and is characterised by defici­ent in­sulin production due to the destruction of ins­u­lin-producing beta cells of the pancreas.

“Ear­lier, pancreas tra­n­spl­an­tations were tr­i­ed, but not regularly. There’s a lack of awareness about it among people and also physicians. This transplantation ca­n­ be done only for type 1 diabetics and that, too, not on everyone. Only a select group of patients needs this,” says Dr N. Sez­h­i­an, senior consultant and transplant surgeon, institute of urology, Glo­bal Health City.

He added that after tra­nsplantation, pat­ien­ts­ can enjoy life without insulin. The hospital is pla­nning to start this tr­a­­­nsplantation.

Panc­r­e­as from a dec­eased do­n­or is transpl­anted to the re­c­i­pient or both kidney and pancreas tog­­­ether are transplanted.
Government Stanley Ho­s­pital is also plann­ing to do pancreas tran­sp­lantations in the fut­ure. A senior doctor poi­n­ted out that stem cell therapy might rep­lace pancreas transplan­ta­­t­ion for type 1 diabe­tes in the near future.

Dr An­a­nd Moses, former director, institute of diabetology, Madras Me­d­­ical Co­l­lege, says that type 1 diabetes constitutes a low number.

“Pa­n­­­­creas can be transpl­anted or insulin secreting cells alone can be tra­­­­nsp­lan­t­ed. But eve­rything is st­i­ll in the early stages and good imm­un­o­sup­pre­s­s­a­nt drugs are needed to prevent rejection,” says Dr Moses, ad­ding that even after tra­nsplan­t­a­t­ion, some of them might require insulin.

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