Cataracts may increase depression symptoms: study

Beijing: Older adults with cataracts are more likely to have symptoms of depression, a new study has found. The link between cataracts and depression is independent of other factors, and appears strongest among older adults with lower education, according to new research by Haifang Wang, of Soochow University in China.

"Our study sheds further light on the complex relationship between ageing, vision loss, cataract, and depression and suggests that there may be a role for cataract surgery in improving mental health in the elderly," researchers said. Age-related cataracts are the leading cause of visual impairment worldwide and are expected to increase as population demographics shift towards advancing age.

Depression is also common in older adults. This large study in Chinese older adults investigated the link between visual impairment and depressive symptoms and provides evidence for an association between cataracts and depression.

As part of a community survey study, approximately 4,600 older adults (60 years or older) in one Chinese town completed a depression questionnaire. Participants also underwent a clinical eye examination to rate the presence and severity of cataracts. Cataracts are a very common condition in older adults, with clouding of the lens of the eye causing vision loss.

Excluding those with previous cataract surgery, nearly half (49 per cent) of older adults in the study had cataracts in at least one eye. On the depression questionnaire, 8 percent of subjects had depressive symptoms. Symptoms of depression were more common in women than men (11 versus 5 per cent), and more common in older age groups.

Older adults with cataracts were more likely to have depressive symptoms, independent of socioeconomic status, lifestyle factors, and visual acuity. On adjusted analysis, symptoms of depression were 33 per cent more likely when cataracts were present. Importantly, the odds of depressive symptoms were similar for subjects with cataracts in one eye versus both eyes.

The association between cataracts and depression was even stronger for subjects with no formal education - a 50 per cent increase. After all other factors were taken into account, cataracts explained 14 per cent of the variation in depression risk.

The researchers note that their study cannot show the direction of the association - vision loss might cause older adults to become isolated and withdrawn, or depression might make them less likely to seek treatment for cataracts. The study was published in the journal Optometry and Vision Science.